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Synaptic pruning, a phase in the development of the nervous system, is the process of synapse elimination that occurs between early childhood and the onset of puberty in many mammals, including humans. [1] Pruning starts near the time of birth and continues into the late-20s. [2]
Synaptogenesis is particularly important during an individual's critical period, during which there is a certain degree of synaptic pruning due to competition for neural growth factors by neurons and synapses. Processes that are not used, or inhibited during their critical period will fail to develop normally later on in life.
Evidence points to teratogens affecting the early developmental stages, suggesting autism arises very early, possibly within the first eight weeks after conception. [12] Neuroanatomical studies support that autism may involve abnormal neuronal growth and pruning, leading to brain enlargement in some areas and reduction in others. [13]
Beth Stevens was born in 1970 in Brockton, Massachusetts.Her mother taught elementary school, and her father was the school's principal. [5]Stevens earned a B.S. in Biology from Northeastern University (1993), where she worked full-time in medical labs through Northeastern's co-op program.
Synaptic defects are causally associated with early appearing neurological diseases, including autism spectrum disorders (ASD), schizophrenia (SCZ), and bipolar disorder (BP). Synaptic dysfunction, or synaptopathy, is often implicated in late-onset neurodegenerative diseases such as Alzheimer's, Parkinson's, and Huntington's, but the exact ...
The article in The Lancet claimed that the measles, mumps, and rubella (MMR) vaccine caused autism. The methodological flaws were readily apparent to followers of medical research: among many ...
Unable to speak, read, or write, Joey was diagnosed with “severe autism,” a neurodevelopmental disability that doctors were still learning about nearly 30 years ago.
Garnet Collins, 51, tortured the teen at the Anderson Center for Autism in upstate Staatsburg, about 10 miles north of Poughkeepsie, where NYC and state taxpayers paid his tuition, room and board.