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Equine recurrent uveitis (ERU) – also known as moon blindness, recurrent iridocyclitis, or periodic ophthalmia [1] – is an acute, nongranulomatous inflammation of the uveal tract of the eye, occurring commonly in horses of all breeds, worldwide. The causative factor is not known, but several pathogeneses have been suggested.
Uveitis in horses has many causes, including eye trauma, disease, and bacterial, parasitic and viral infections, but ERU is characterized by recurring episodes of uveitis, rather than a single incident.
Uveitis: is a group of 30 intraocular inflammatory diseases [71] caused by infections, systemic diseases, organ-specific autoimmune processes, cancer or trauma. [72] That is, uveitis refers to a complex category of ocular diseases that can cause blindness if either left untreated or improperly diagnosed. [72]
Uveitis includes recurrent uveitis and periodic ophthalmia ("moon blindness"). Spontaneous equine recurrent uveitis (ERU) occurs in 10-15% of the equine population, with the Appaloosa breed having an eightfold higher risk than the general horse population. [23] Habronema; Keratoconjunctivitis sicca
People taking Ozempic and Wegovy may be at increased risk of developing a debilitating eye condition that can cause irreversible vision loss, a study published in JAMA Ophthalmology finds.
Uveitis is estimated to be responsible for approximately 10%-20% of the blindness in the United States. [ 36 ] For non-infectious uveitis, women are more likely (57%) to be affected than men, possibly due to their higher prevalence of related autoimmune diseases . [ 37 ]
Uveitis in horses has many causes, including eye trauma, disease, and bacterial, parasitic and viral infections, but ERU is characterized by recurring episodes of uveitis, rather than a single incident.
For this reason, blindness in animals is a unique topic of study. In general, nocturnal or subterranean animals have less interest in the visual world, and depend on other sensory modalities . Visual capacity is a continuum, with humans falling somewhere in the center.