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The effective population size (N e) is the size of an idealised population that would experience the same rate of genetic drift as the real population. [1] Idealised populations are those following simple one- locus models that comply with assumptions of the neutral theory of molecular evolution .
It is a measure of the "population mutation rate" (the product of the effective population size and the neutral mutation rate) from the observed nucleotide diversity of a population. θ = 4 N e μ {\displaystyle \theta =4N_{e}\mu } , [ 3 ] where N e {\displaystyle N_{e}} is the effective population size and μ {\displaystyle \mu } is the per ...
For example, let the design effect, for estimating the population mean based on some sampling design, be 2. If the sample size is 1,000, then the effective sample size will be 500. It means that the variance of the weighted mean based on 1,000 samples will be the same as that of a simple mean based on 500 samples obtained using a simple random ...
where u is the mutation rate, and N e is the effective population size. The effective number of alleles n maintained in a population is defined as the inverse of the homozygosity, that is = = + which is a lower bound for the actual number of alleles in the population. If the effective population is large, then a large number of alleles can be ...
Genetic draft results in similar behavior to the equation above, but with an effective population size that may have no relationship to the actual number of individuals in the population. [3] Instead, the effective population size may depend on factors such as the recombination rate and the frequency and strength of beneficial mutations.
In population genetics and population ecology, population size (usually denoted N) is a countable quantity representing the number of individual organisms in a population. Population size is directly associated with amount of genetic drift , and is the underlying cause of effects like population bottlenecks and the founder effect . [ 1 ]
Huff et al. (2010) rejected all models with an ancient effective population size larger than 26,000. [9] For ca. 130,000 years ago, Sjödin et al. (2012) estimate an effective population size of the order of 10,000 to 30,000 individuals, and infer an actual "census population" of early Homo sapiens of roughly 100,000 to 300,000 individuals. [ 10 ]
Effective number of codons (abbreviated as ENC or Nc) is a measure to study the state of codon usage biases in genes and genomes. [1] The way that ENC is computed has obvious similarities to the computation of effective population size in population genetics . [ 2 ]