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  2. Prazosin - Wikipedia

    en.wikipedia.org/wiki/Prazosin

    Prazosin, sold under the brand name Minipress among others, is a medication used to treat high blood pressure, symptoms of an enlarged prostate, and nightmares related to post-traumatic stress disorder (PTSD). [6] It is an α 1 blocker. [6] It is a less preferred treatment of high blood pressure. [6] Other uses may include heart failure and ...

  3. Alpha blocker - Wikipedia

    en.wikipedia.org/wiki/Alpha_blocker

    High doses of the α 1 blocker, prazosin, have been efficacious in treating patients with PTSD induced nightmares due to its ability to block the effects of norepinephrine. [27] Adverse effects of prazosin to treat PTSD nightmares include dizziness, first dose effect (a sudden loss of consciousness), weakness, nausea, and fatigue. [27]

  4. Alpha-1 blocker - Wikipedia

    en.wikipedia.org/wiki/Alpha-1_blocker

    The risk of first dose phenomenon may be reduced or eliminated by gradual-dose titration, since the adverse effects of Prazosin are dose-related. [7] This is also the case for Tamsulosin and it may be assumed that the others alpha-1 blockers work in a similar manner, since Tamsulosin is an alpha-1-a blocker and Prazosin is an alpha-1 blocker. [30]

  5. First-dose phenomenon - Wikipedia

    en.wikipedia.org/wiki/First-dose_phenomenon

    This postural hypotension usually happens shortly after the first dose is absorbed into the blood and can result in syncope (fainting). Syncope occurs in approximately 1% of patients given an initial dose of 2 mg prazosin or greater. This adverse effect is self-limiting and in most cases does not recur after the initial period of therapy or ...

  6. Review links 3 potentially-blinding eye conditions to GLP-1 ...

    www.aol.com/review-links-3-potentially-blinding...

    A new review reports that nine people taking semaglutide and tirzepatide — the active ingredient in GLP-1 medications — experienced vision issues, including three potentially blinding eye ...

  7. If You Spot This Creature, Run! - AOL

    www.aol.com/lifestyle/spot-creature-run...

    Nature’s anything but a safe place. Some of the creatures you’ll find out there are straight-up biological weapons. Get ready for some good nightmares tonight, because we’re bringing you ...

  8. List of drugs known for off-label use - Wikipedia

    en.wikipedia.org/wiki/List_of_drugs_known_for...

    Prazosin (Minipress) for nightmares: prazosin is approved for the use of hypertension. A 2012 systematic review showed a small benefit for the treatment of PTSD-associated night terrors. Other non-FDA-approved uses for prazosin include the treatment of Raynaud's disease and poisoning due to scorpion venom.

  9. It feels like there are suddenly way more plane crashes and ...

    www.aol.com/feels-suddenly-way-more-plane...

    The wreckage of a Delta Air Lines-operated CRJ900 aircraft lays on the runway after a plane crash at Toronto Pearson International Airport. - Cole Burston/Reuters