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Methylephedrine, sold under the brand name Metheph among others, is a sympathomimetic medication described as an antiasthmatic agent and used to treat coughing and nasal congestion. [ 3 ] [ 4 ] [ 1 ] It is reported to be used in various over-the-counter cough and cold preparations throughout the world, including Japan .
Levmetamfetamine is used to treat nasal congestion related to the common cold and allergic rhinitis. It is available in the form of an inhaler containing 50 mg total per inhaler and delivering between 0.04 and 0.15 mg of the drug per inhalation. [2]
Their effectiveness by themselves in the common cold appears to have a small benefit in adults. [1] Topical decongestants should only be used by patients for a maximum of 5–7 days in a row, because rebound congestion may occur in the form of rhinitis medicamentosa. When used in adults for a short period of time side effects appear to be few. [1]
Phenylpropanolamine was previously available in the United States over-the-counter and in certain combination drug forms by prescription. [24] [25] One such example of the latter was a combination of phenylpropanolamine and chlorpheniramine, which dually contained decongestant and antihistamine effects, marketed by Tutag as 'Vernate'.
Levomethamphetamine, also known as levmetamfetamine or l-desoxyephedrine, and sold under the brand name Vicks VapoInhaler among others, is an optical isomer of methamphetamine primarily used as a topical nasal decongestant. [2]
Phenylephrine, sold under the brand names Neosynephrine and Sudafed PE among others, is a medication used as a decongestant for uncomplicated nasal congestion in the form of a nasal spray or oral tablet, [5] to dilate the pupil, to increase blood pressure given intravenously in cases of low blood pressure, and to relieve hemorrhoids as a suppository.
The range contains 200 mg of guaifenesin which helps to relieve chesty cough, in addition to 1000 mg of paracetamol and 12.2 mg of phenylephrine hydrochloride (12.18 mg of phenylephrine hydrochloride in Lemsip Max All In One Liquid) which aims to relieve headache, sore throat, fever, body aches and pains, and a blocked nose.
Propylhexedrine works mainly as an adrenergic agonist, when used at therapeutic doses in an inhaler dosage form. [21] This restricts the blood vessels in the nose and reduces swelling; thereby, it relieves nasal congestion. [22] At higher doses, propylhexedrine affects the central nervous system as a norepinephrine–dopamine releasing agent ...