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  2. Neural stem cell - Wikipedia

    en.wikipedia.org/wiki/Neural_stem_cell

    Neural stem cells differentiating to astrocytes (green) and sites of growth hormone receptor shown in red. There are two basic types of stem cell: adult stem cells, which are limited in their ability to differentiate, and embryonic stem cells (ESCs), which are pluripotent and have the capability of differentiating into any cell type.

  3. Adult neurogenesis - Wikipedia

    en.wikipedia.org/wiki/Adult_neurogenesis

    Adult neurogenesis is the process in which neurons are generated from neural stem cells in the adult. This process differs from prenatal neurogenesis . In most mammals, new neurons are born throughout adulthood in two regions of the brain: [ 3 ]

  4. Neurogenesis - Wikipedia

    en.wikipedia.org/wiki/Neurogenesis

    Most of these adult neural stem cells lie dormant in the adult, but in response to certain signals, these dormant cells, or B cells, go through a series of stages, first producing proliferating cells, or C cells. The C cells then produce neuroblasts, or A cells, that will become neurons. [16]

  5. PI3K/AKT/mTOR pathway - Wikipedia

    en.wikipedia.org/wiki/PI3K/AKT/mTOR_pathway

    Neural stem cells (NSCs) in the brain must find a balance between maintaining their multipotency by self renewing and proliferating as opposed to differentiating and becoming quiescent. The PI3K/AKT pathway is crucial in this decision making process. NSCs are able to sense and respond to changes in the brain or throughout the organism.

  6. Development of the nervous system - Wikipedia

    en.wikipedia.org/wiki/Development_of_the_nervous...

    Neurogenesis is the process by which neurons are generated from neural stem cells and progenitor cells. Neurons are 'post-mitotic', meaning that they will never divide again for the lifetime of the organism. [11] Epigenetic modifications play a key role in regulating gene expression in differentiating neural stem cells and are critical for cell ...

  7. Stem-cell therapy - Wikipedia

    en.wikipedia.org/wiki/Stem-cell_therapy

    There is other stem cell research that does not involve the destruction of a human embryo, and such research involves adult stem cells, amniotic stem cells, and induced pluripotent stem cells. In January 2009, the US Food and Drug Administration gave clearance to Geron Corporation for the first clinical trial of an embryonic stem-cell-based ...

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