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Finasteride is also used to treat male pattern baldness (androgenic alopecia) in men, a condition that develops in up to 80% of Caucasian men aged 70 and over. [ 24 ] [ 4 ] In the United States, finasteride and minoxidil are the only two FDA approved drugs for the treatment of male pattern hair loss as of 2017. [ 25 ]
A clinical study that compared the effects of oral finasteride against a finasteride 0.25% topical solution was carried out on 24 men with androgenetic alopecia.
In comparison, the rate of improvement was 80.5 percent for men who used finasteride and just 59 percent for men who only used minoxidil. You may have heard of topical minoxidil under the brand ...
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Other 5α-reductase inhibitors such as finasteride (a type 2 inhibitor) have been used off-label to treat excessive hair growth in women with hirsutism. [ 3 ] [ 23 ] Since dutasteride is an inhibitor of both type 1 and 2 5α-reductases, it could theoretically be a more effective therapy for hirsutism.
5α-Reductase inhibitors like finasteride, dutasteride, and alfatradiol and the topical nonsteroidal AR antagonist topilutamide (fluridil) are approved for the treatment of pattern hair loss, also known as scalp hair loss or baldness. [40] This condition is generally caused by androgens, so antiandrogens can slow or halt its progression. [41]
Hair Loss in Women It’s normal to lose about 50 to 100 hairs a day . But it can be upsetting when you notice more hair loss than this, bald patches, a widening part, or a ponytail that keeps ...
GnRH antagonists are being investigated in the treatment of women with hormone-sensitive breast cancer. [ 8 ] [ 9 ] In men, they are being investigated in the treatment of benign prostatic hyperplasia [ 10 ] and also as potential contraceptive agents. [ 11 ]
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