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Malaria can be a severe, potentially fatal disease, especially when caused by Plasmodium falciparum. Ensure prompt diagnosis followed by immediate treatment. The treatment regimen depends on infecting plasmodium species, patient's clinical status, drug-resistance status, and previous use of antimalarials. In the absence of prompt diagnosis and ...
Malaria is a medical emergency and can become life-threatening if not quickly diagnosed and appropriately treated. Only a healthcare provider can diagnose and treat a patient for malaria. Prescription drugs, available in the U.S., can cure malaria.
Use the Malaria Treatment Tables (Tables 1 – 4) for specific drug and dosing recommendations for uncomplicated malaria. To prevent future relapses, P. vivax and P. ovale infections require treatment to kill dormant hypnozoites in addition to treatment for the acute phase of malaria.
Recommendations for drugs to prevent malaria differ by country of travel and can be found in CDC's Yellow Book chapter on Malaria Prevention Information, by Country. Recommended drugs for each country are listed in alphabetical order and have comparable efficacy in that country.
Guide patient treatment by Plasmodium species, patient's clinical status, expected drug susceptibility of infecting parasite, and previous use of antimalarials. Use the Malaria Treatment Tables for drug recommendations, as well as adult and pediatric dosing.
The CDC’s Algorithm for Diagnosis and Management of Malaria provides guidance on the recommended steps to adequately assess and treat malaria patients.
* Treatment for special populations (children and pregnant women) can be found in the CDC Treatment Guidelines and Treatment Table. ** If rapid diagnostic test performed, smear should also be performed with results available as soon as possible.
Prevention. Avoiding mosquito bites and taking appropriate medications is the best way to prevent malaria. Malaria Topics. Clinical Features. Malaria infection is caused by Plasmodium parasite species and can be uncomplicated or severe. Clinical Guidance: Malaria Diagnosis & Treatment in the U.S.
A 3-day treatment schedule with a total of 6 oral doses is recommended for both adult and pediatric patients based on weight. The patient should receive the initial dose, followed by the second dose 8 hours later, then 1 dose po bid for the following 2 days. 5 - <15 kg: 1 tablet per dose.
CDC recommends a primaquine phosphate dose of 30 mg (base) by mouth daily for 14 days. Because primaquine can cause hemolytic anemia in persons with glucose-6-phosphate-dehydrogenase (G6PD) deficiency, persons must be screened for G6PD deficiency prior to starting primaquine treatment.