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Hypersalivation or hypersialosis is the excessive production of saliva. [3] It has also been defined as increased amount of saliva in the mouth, which may also be caused by decreased clearance of saliva.
Velufenacin (DA-8010) is a muscarinic antagonist that operates on the M3 receptor and is tissue-selective for bladder over salivary glands. It is in development as a treatment for overactive bladder. [1] [2] [3] [4]
Sialoendoscopy is a minimally invasive technique that allows for salivary gland surgery for the safe and effective treatment of obstructive salivary gland disorders and other conditions of the salivary glands. During sialoendoscopy a small endoscope is placed into the salivary glands through the salivary ducts that empty into the mouth.
Salivary gland dysfunction affects the flow, amount, or quality of saliva produced. A reduced salivation is termed hyposalivation . Hyposalivation often results in a dry mouth condition called xerostomia , and this can cause tooth decay due to the loss of the protective properties of saliva.
The two parotid glands are major salivary glands wrapped around the mandibular ramus in humans. [6] These are largest of the salivary glands, secreting saliva to facilitate mastication and swallowing, and amylase to begin the digestion of starches. [7] It is the serous type of gland which secretes alpha-amylase (also known as ptyalin). [8]
Sialodochitis (also termed ductal sialadenitis), [1] is inflammation of the duct system of a salivary gland. [2] This is compared to sialadenitis, which is inflammation of the gland parenchyma. [3] Sialodochitis may be associated with salivary duct strictures and salivary stones. [4] It is common in both the parotid glands and submandibular ...
Sialolithiasis (also termed salivary calculi, [1] or salivary stones) [1] is a crystallopathy where a calcified mass or sialolith forms within a salivary gland, usually in the duct of the submandibular gland (also termed "Wharton's duct"). Less commonly the parotid gland or rarely the sublingual gland or a minor salivary gland may develop ...
Saliva stagnates and forms a mucus plug behind the stricture during sleep when the salivary output of the parotid is reduced. Then, when salivary secretion is stimulated, the mucus plug becomes stuck in the stricture. [1] The backlog of saliva behind the blockage causes the swelling, and the increased pressure inside the gland causes the pain.