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There is no general agreement about the intake levels at which vitamin D may cause harm. According to the IOM review, "Doses below 10,000 IU/day are not usually associated with toxicity, whereas doses equal to or above 50,000 IU/day for several weeks or months are frequently associated with toxic side effects including documented hypercalcemia."
Vitamin D3, aka cholecalciferol, is important for bone health and immune function. Experts discuss benefits, sources, risks and who needs a supplement. How to get the most out of vitamin D3
Vitamin D compounds, specifically cholecalciferol (D3) and ergocalciferol (D2) are used in rodenticides due to their ability to induce hypercalcemia, a condition characterized by elevated calcium levels in the blood. This overdose leads to organ failure and is pharmacologically similar to vitamin D's toxic effects in humans.
Vitamin D (the inactive version) is mainly from two forms: vitamin D 3 and vitamin D 2. Vitamin D 3, or cholecalciferol, is formed in the skin after exposure to sunlight or ultra violet radiation or from D 3 supplements or fortified food sources. Vitamin D 2, or ergocalciferol, is obtained from D 2 supplements or fortified food sources. [3]
There's lots of confusion around the difference between vitamin D2 and vitamin D3, and which is best for whom. Doctors and experts explain.
Mapping of several bone diseases onto levels of vitamin D (calcidiol) in the blood [6] Normal bone vs. osteoporosis. Vitamin D deficiency is typically diagnosed by measuring the concentration of the 25-hydroxyvitamin D in the blood, which is the most accurate measure of stores of vitamin D in the body.