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Treatment with oral tyrosine kinase inhibitor drugs (e.g. imatinib, sorafenib, pazopanib, sunitinib) shows promising success rates. [43] [29] [44] [40] [45] Radiation therapy after surgery may improve outcomes. [15] [45] Despite the condition's hormonal link, anti-hormonal therapies only appear to work in a small subset of patients. [15]
Manual work: [24] [29] a 2023 paper by researchers at the University of Groningen Medical Centre and Oxford University, "Dupuytren's disease is a work-related disorder: results of a population-based cohort study", found that people whose jobs involved significant manual work were 1.29 times more likely to develop Dupuytren's disease than others ...
1 × 10 ^ 2: 5 years: 2.3: Canada CNSC occupational limit over a 5-year dosimetry period for designated Nuclear Energy Workers [9] 100 1 × 10 ^ 2: Acute-USA EPA acute dose level estimated to increase cancer risk 0.8% [6] 120 1.2 × 10 ^ 2: 30 years: 0.46: Exposure, long duration, Ural Mountains, lower limit, lower cancer mortality rate [13 ...
It is the absorbed energetic dose before the biological efficiency of the radiation is factored in. The rep has variously been defined as 83 or 93 ergs per gram of tissue (8.3/9.3 mGy) [2] or per cm 3 of tissue. [3] At the time, this was thought to be the amount of energy deposited by 1 roentgen. [4]
Therapeutic radiation increases the risk of a subsequent cardiovascular event (i.e., heart attack or stroke) by 1.5 to 4 times a person's normal rate, aggravating factors included. [34] The increase is dose dependent, related to the RT's dose strength, volume and location.
Radiosurgery is surgery using radiation, [1] that is, the destruction of precisely selected areas of tissue using ionizing radiation rather than excision with a blade. Like other forms of radiation therapy (also called radiotherapy), it is usually used to treat cancer.
[clarification needed] Head and neck desmoid fibromatosis is a serious condition due to local aggression, specific anatomical patterns and the high rate of relapse. For children surgery is particularly difficult, given the potential for growth disorders. [6] Treatment includes prompt radical excision with a wide margin and/or radiation.
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