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Eating amygdalin will cause it to release cyanide in the human body, and may lead to cyanide poisoning. [ 1 ] Since the early 1950s, both amygdalin and a chemical derivative named laetrile have been promoted as alternative cancer treatments , often under the misnomer vitamin B 17 (neither amygdalin nor laetrile is a vitamin ). [ 2 ]
Cyanide is a potent cytochrome c oxidase (COX, a.k.a. Complex IV) inhibitor, causing asphyxiation of cells. As such, cyanide poisoning is a form of histotoxic hypoxia, because it interferes with the ability of cells to take or use oxygen via oxidative phosphorylation. [25]: 1475
The severity of the health risks depend on how cherry pits are consumed. All of the harmful amygdalin is stored in the center of the pit, so the kernel surrounding it acts as a protective coating.
Removal of cyanide from cassava in Nigeria. Cyanides are produced by certain bacteria, fungi, and algae.It is an antifeedant in a number of plants. Cyanides are found in substantial amounts in certain seeds and fruit stones, e.g., those of bitter almonds, apricots, apples, and peaches. [5]
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The seeds, unripened arils, and inedible portions of the ackee fruit contain the toxins hypoglycin A and hypoglycin B, which inhibit enzymes involved in fatty acid metabolism and thereby cause a depletion of stored glucose, which is necessary to meet the body's energy needs, and in turn leads to hypoglycemia. [6] Citrus spp.
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