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4-Piperidone is an organic compound with the molecular formula OC(CH 2) 4 NH. It can be viewed as a derivative of piperidine. 4-Piperidone is used as an intermediate in the manufacture of chemicals and pharmaceutical drugs. Substituted and dehydro derivatives of 4-piperidinone are intermediates in alkaloid syntheses. [1]
The tert-butyloxycarbonyl protecting group or tert-butoxycarbonyl protecting group [1] (BOC group) is an acid-labile protecting group used in organic synthesis. The BOC group can be added to amines under aqueous conditions using di- tert -butyl dicarbonate in the presence of a base such as sodium hydroxide :
Piperidine is an organic compound with the molecular formula (CH 2) 5 NH. This heterocyclic amine consists of a six-membered ring containing five methylene bridges (–CH 2 –) and one amine bridge (–NH–). It is a colorless liquid with an odor described as objectionable, typical of amines. [6]
N-benzyl-4-piperidone fentanyl: chloroephedrine methamphetamine Butyrophenone: substituted cathinones: Valerophenone: substituted cathinones: Propiophenone: substituted cathinones: 2C-H: 2C-x and DOx: 2-bromo-1-(4-chlorophenyl)propan-1-one substituted cathinones and substituted amphetamines: 2-bromo-1-(4-methoxyphenyl)propan-1-one
N-Phenethyl-4-piperidinone (NPP) is a derivative of 4-piperidinone with the molecular formula C 13 H 17 NO. It is used as an intermediate in the manufacture of chemicals and pharmaceutical drugs such as fentanyl .
The synthesis of 6-acetyl-1,2,3,4-tetrahydropyridine, an important bread aroma compound, starting from 2-piperidone was accomplished using t-boc anhydride. [14] See Maillard reaction ). The first step in this reaction sequence is the formation of the carbamate from the reaction of the amide nitrogen with boc anhydride in acetonitrile using DMAP ...
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2-Piperidinone (2-piperidone or δ-valerolactam) is an organic compound with the formula (CH 2) 4 CONH. Valerolactam is formed by dehydrogenation of 5-amino-1-pentanol, catalyzed by rhodium and ruthenium complexes, [3] [4] The compound, a colorless solid, is classified as a lactam. It is the monomer of nylon 5, a polyamide: n (CH 2) 4 CONH → ...