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This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.
Pages in category "Monoclonal antibodies" The following 200 pages are in this category, out of approximately 307 total. This list may not reflect recent changes .
Anti-CD20 antibody. Chronic lymphocytic leukaemia: Neutropenia, pneumonia, infusion reactions, cytopenias Panitumumab: IV: EGFR inhibitor. RAS (KRAS or NRAS) wild-type metastatic colorectal cancer: Skin reactions, electrolyte anomalies, anaphylaxis and angiooedema (rare). Pembrolizumab: IV: Anti-PD-1 monoclonal antibody.
Antibody-directed enzyme prodrug therapy (ADEPT) involves the application of cancer-associated monoclonal antibodies that are linked to a drug-activating enzyme. Systemic administration of a non-toxic agent results in the antibody's conversion to a toxic drug, resulting in a cytotoxic effect that can be targeted at malignant cells.
He is a true translational investigator, since he used these monoclonal antibodies to classify human B-cell leukemia and lymphomas as well as to create therapeutic agents for patients. . . More importantly, he was the first in the world to administer a monoclonal antibody to a human (a patient with B-cell lymphoma)." [11]
Pages in category "Drugs that are a monoclonal antibody" The following 200 pages are in this category, out of approximately 482 total. This list may not reflect recent changes .
This page was last edited on 18 September 2013, at 12:51 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.
Bi-specific T-cell engager (BiTE) is a class of artificial bispecific monoclonal antibodies that are investigated for use as anti-cancer drugs. They direct a host's immune system, more specifically the T cells ' cytotoxic activity, against cancer cells.