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[1] Another factor is the duration of exposure. Some drugs or supplements have a slow-release feature in which portions of the medication are metabolized at different times, which changes the impacts the active ingredients have on the body. Some substances are meant to be taken in small doses over large periods of time to maintain a constant ...
Although designed primarily for drug utilisation research, data using the DDD can only give a "rough estimate" compared with actually collecting statistics on drug use in practice. [1] The DDD is often use for long term research and analysis of drug utilisation trends over time, so changes to the DDD are avoided if possible, [ 3 ] whereas ...