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Hypophosphatemic rickets are associated with at least nine other genetic mutations. [14] Clinical management of hypophosphatemic rickets may differ depending on the specific mutations associated with an individual case, but treatments are aimed at raising phosphate levels to promote normal bone formation. [15]
Osteomalacia in children is known as rickets, and because of this, use of the term "osteomalacia" is often restricted to the milder, adult form of the disease. Signs and symptoms can include diffuse body pains, muscle weakness, and fragility of the bones.
For treating rickets, the American Academy of Pediatrics (AAP) has recommended that pediatric patients receive an initial two to three months of treatment with "high-dose" vitamin D therapy. In this regime, the daily dose of cholecalciferol is 1000 IU for newborns, 1000 to 5000 IU for 1- to 12-month-old infants, and 5000 IU for patients over 1 ...
[2] [3] The analogous condition in adults is osteomalacia. The most common cause of rickets is a vitamin D deficiency , although hereditary genetic forms also exist. [ 2 ] This can result from eating a diet without enough vitamin D , dark skin, too little sun exposure, exclusive breastfeeding without vitamin D supplementation, celiac disease ...
InterContinental Hotels Group (IHG), marketed as IHG Hotels & Resorts, is a British multinational hospitality company headquartered in Windsor, Berkshire, England. [4] It is listed on the London Stock Exchange and the New York Stock Exchange . [ 5 ]
Founded in 1981 by Bill Kimpton and led by Chief Executive Officer Mike DeFrino, the group was the largest chain of boutique hotels in the United States in 2011. As of January 2024, it operates 81 hotels worldwide with a number of new properties forthcoming. [2]
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Hotel Indigo is a global brand group of small, individually owned boutique hotels, which is part of IHG Hotels & Resorts (InterContinental Hotels Group). As of June 2024 it has 156 hotels with over 20,000 rooms worldwide, and has stated that it plans to open more than 150 further hotels.