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Adult onset of Kawasaki disease is rare. [50] The presentation differs between adults and children: in particular, it seems that adults more often have cervical lymphadenopathy, hepatitis, and arthralgia. [32] [50] Some children, especially young infants, [51] have atypical presentations without the classic set of symptoms. [48]
Kawasaki disease is most commonly seen in infants and children under five years old and is more likely to affect boys. The disease is self-limited which means that the inflammation will resolve after 6 to 8 weeks but if we left it untreated, there is a 20-25% risk of the heart complications we went over. Alright so let’s look at the symptoms ...
Acquired causes include atherosclerosis in adults, [4] Kawasaki disease in children [5] and coronary catheterization. With the invention of drug eluting stents, there has been more cases implying stents lead to coronary aneurysms. The pathophysiology, although not completely understood, might be comparable to that of aneurysms of larger vessels.
In addition, MAS has been described in association with systemic lupus erythematosus (SLE), Kawasaki disease, and adult-onset Still's disease. It is thought to be closely related and pathophysiologically very similar to reactive (secondary) hemophagocytic lymphohistiocytosis (HLH). [1]
Diagnosis of arteritis is based on unusual medical symptoms. [4] Similar symptoms may be caused by a number of other conditions, such as Ehlers-Danlos syndrome and Marfan syndrome (both heritable disorders of connective tissue), tuberculosis, syphilis, spondyloarthropathies, Cogans' syndrome, Buerger's, Behcet's, and Kawasaki disease. [4]
The disease's symptoms can range from catastrophic neurological impairment to an asymptomatic condition brought on by impalpable pulses or bruits. [7] Non-specific features include mild anemia, myalgia, arthralgia, weight loss, malaise, night sweats, and fever. [8] Giant cell arteritis (GCA) is the most common type of systemic vasculitis in adults.
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Multisystem inflammatory syndrome may refer to: . Multisystem inflammatory syndrome in children (also known as 'paediatric multisystem inflammatory syndrome', or 'paediatric inflammatory multisystem syndrome' - 'PIMS'), a rare life-threatening illness resembling Kawasaki disease that has been observed following exposure to the virus responsible for COVID-19; [1] [2] [3] while a similar ...