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Gabapentin, sold under the brand name Neurontin among others, is an anticonvulsant medication primarily used to treat partial seizures and neuropathic pain. [ 7 ][ 10 ] It is a commonly used medication for the treatment of neuropathic pain caused by diabetic neuropathy, postherpetic neuralgia, and central pain. [ 11 ]
Gabapentinoid. Gabapentinoids, also known as α2δ ligands, are a class of drugs that are derivatives of the inhibitory neurotransmitter gamma-Aminobutyric acid (GABA) (i.e., GABA analogues) which block α 2 δ subunit -containing voltage-dependent calcium channels (VDCCs). [1][2][3][4] This site has been referred to as the gabapentin receptor ...
Anticonvulsant. Anticonvulsants (also known as antiepileptic drugs, antiseizure drugs, or anti-seizure medications (ASM)) are a diverse group of pharmacological agents used in the treatment of epileptic seizures. [ 1 ] Anticonvulsants are also increasingly being used in the treatment of bipolar disorder [ 2 ][ 3 ] and borderline personality ...
The link between gabapentin and ED may be due to gabapentin’s effects on neurotransmitters. Gabapentin is also associated with other intimate side effects, like difficulty reaching orgasm ...
Uranium-235 (235U or U-235) is an isotope of uranium making up about 0.72% of natural uranium. Unlike the predominant isotope uranium-238, it is fissile, i.e., it can sustain a nuclear chain reaction. It is the only fissile isotope that exists in nature as a primordial nuclide. Uranium-235 has a half-life of 703.8 million years.
Pregabalin, sold under the brand name Lyrica among others, is an anticonvulsant, analgesic, and anxiolytic amino acid medication used to treat epilepsy, neuropathic pain, fibromyalgia, restless legs syndrome, opioid withdrawal, and generalized anxiety disorder (GAD).
In the natural environment, radioactivity of uranium is generally low, [1] but uranium is a toxic metal that can disrupt normal functioning of the kidney, brain, liver, heart, and numerous other systems. [2] Chemical toxicity can cause public health issues when uranium is present in groundwater, especially if concentrations in food and water ...
Natural uranium contains about 0.72% 235 U. Depleted uranium has lower mass fractions—up to three times less—of 235 U and 234 U than natural uranium. Since 238 U has a much longer half-life than the lighter isotopes, DU is about 40% less radioactive than natural uranium.