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Postherpetic neuralgia (PHN) is neuropathic pain that occurs due to damage to a peripheral nerve caused by the reactivation of the varicella zoster virus (herpes zoster, also known as shingles). PHN is defined as pain in a dermatomal distribution that lasts for at least 90 days after an outbreak of herpes zoster. [ 1 ]
Gabapentin, sold under the brand name Neurontin among others, is an anticonvulsant medication primarily used to treat neuropathic pain and also for partial seizures [10] [7] of epilepsy. It is a commonly used medication for the treatment of neuropathic pain caused by diabetic neuropathy, postherpetic neuralgia, and central pain. [11]
Gabapentin, under the brand name Neurontin, was first approved in May 1993 for the treatment of epilepsy in the United Kingdom, and was marketed in the United States in 1994. [43] [44] Subsequently, gabapentin was approved in the United States for the treatment of postherpetic neuralgia in May 2002. [45]
Symptomatic treatment is often needed for the complication of postherpetic neuralgia. [65] However, a study on untreated shingles shows that, once the rash has cleared, postherpetic neuralgia is very rare in people under 50 and wears off in time; in older people, the pain wore off more slowly, but even in people over 70, 85% were free from pain ...
PHN: postherpetic neuralgia: PHP: Partial Hospitalization Program: PHQ: Patient Health Questionnaire: PHTLS: prehospital trauma life support PI: present illness PICC: peripherally inserted central catheter: PID: pelvic inflammatory disease prolapsed intervertebral disc: PIG-A: phosphatidyl inositol glycan A PIH: pregnancy induced hypertension ...
ATN symptoms may also be similar to those of post-herpetic neuralgia, which causes nerve inflammation when the latent herpes zoster virus of a previous case of chicken pox re-emerges in shingles. Fortunately, post-herpetic neuralgia is generally treated with medications that are also the first medications tried for ATN, which reduces the ...