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A biologic form of surgical mesh called biomesh has been used in inguinal and other types of hernia surgeries, particular in contaminated fields.. Biomesh (or biologic mesh) is a type of surgical mesh made from an organic biomaterial (such as porcine dermis, porcine small intestine submucosa, bovine dermis or pericardium, and the dermis or fascia lata of a cadaveric human).
Surgical mesh can be made from both inorganic and biological materials and is used in a variety of surgeries, although hernia repair is the most common application. It can also be used for reconstructive work, such as in pelvic organ prolapse [ 1 ] or to repair physical defects (mainly of body cavity walls) created by extensive resections or ...
Inguinal hernia surgery is an operation to repair a weakness in the abdominal wall that abnormally allows abdominal contents to slip into a narrow tube called the inguinal canal in the groin region. There are two different clusters of hernia: groin and ventral (abdominal) wall. Groin hernia includes femoral, obturator, and inguinal. [1]
The rate of recurrence ranged from 1.1 to 18.8% for synthetic mesh. The rate of recurrence ranged from 0 to 15.4% for biologic mesh. The reviewers stated that the risk of mesh related complications are low for both synthetic and biologic mesh, and there may a small reduction in mesh-related complications with biologic mesh.
The UBM is offered in both sheet and powder form. The powder form is sold under the brand name of MicroMatrix. The company offers products for wound management (Cytal and MicroMatrix), hernia repair (Gentrix) and Pelvic Organ Prolapse repair (Pelvic Floor Matrix). Over 100 papers have been published related to the use of ACell's MatriStem UBM.
At present, hernia operations rely heavily on non-degradable polypropylene, polytetrafluoroethylene and nylon meshes. Complications associate with meshes include “adverse reactions to the mesh, adhesions (when the loops of the intestines adhere to each other or the mesh), and injuries to nearby organs, nerves or blood vessels.
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Inguinal hernia repair with mesh diagram Laparoscopic hernia repair with mesh. Surgery is recommended for some types of hernias to prevent complications such as obstruction of the bowel or strangulation of the tissue, although umbilical hernias and hiatus hernias may be watched, or are treated with medication. [34]