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A perfusionist in front of a heart–lung machine (upper right) early in a coronary artery bypass surgery. A cardiovascular perfusionist, clinical perfusionist or perfusiologist, and occasionally a cardiopulmonary bypass doctor [1] [2] or clinical perfusion scientist, [3] is a healthcare professional who operates the cardiopulmonary bypass machine (heart–lung machine) during cardiac surgery ...
A Lindbergh perfusion pump, c. 1935, an early device for simulating natural perfusion. Perfusion is the passage of fluid through the circulatory system or lymphatic system to an organ or a tissue, [1] usually referring to the delivery of blood to a capillary bed in tissue. Perfusion may also refer to fixation via perfusion, used in histological ...
When the heart contracts during systole, the contraction compresses the coronary arteries, which prevents perfusion. Therefore, it is only when the heart relaxes, during diastole , that the coronary vessels open up and allow for perfusion; thus CPP is highest during diastole, unlike most other arteries, which experience higher perfusion ...
As a result, most myocardial perfusion occurs during heart relaxation when the subendocardial coronary vessels are open and under lower pressure. Flow never comes to zero in the right coronary artery, since the right ventricular pressure is less than the diastolic blood pressure.
The first uses a cardiopulmonary bypass machine, a machine which takes over the functions of the heart and lungs during surgery by circulating blood and oxygen. With the heart in cardioplegic arrest, harvested arteries and veins are used to connect across problematic regions—a construction known as surgical anastomosis.
Ventilation–perfusion coupling is the relationship between ventilation and perfusion in the respiratory and cardiovascular systems. [1] Ventilation is the movement of air in and out of the lungs during breathing. [2] Perfusion is the process of pulmonary blood circulation, which reoxygenates blood, allowing it to transport oxygen to body tissues.
Myocardial perfusion imaging or scanning (also referred to as MPI or MPS) is a nuclear medicine procedure that illustrates the function of the heart muscle (). [1]It evaluates many heart conditions, such as coronary artery disease (CAD), [2] hypertrophic cardiomyopathy and heart wall motion abnormalities.
Reperfusion injury, sometimes called ischemia-reperfusion injury (IRI) or reoxygenation injury, is the tissue damage caused when blood supply returns to tissue (re-+ perfusion) after a period of ischemia or lack of oxygen (anoxia or hypoxia).