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The increase in pulse pressure may result in increased damage to blood vessels in target organs such as the brain or kidneys. [ 23 ] [ 24 ] This effect may be exaggerated if the increase in arterial stiffness results in reduced wave reflection and more propagation of the pulsatile pressure into the microcirculation .
Inflammaging is thought to be caused by a loss of control over systemic inflammation resulting in chronic overstimulation of the innate immune system. Inflammaging is a significant risk factor in mortality and morbidity in aged individuals. [2] [3] [4] Inflammation is essential to protect against viral and bacterial infection, as well as ...
In terms of environmental factors, dietary salt intake is the leading risk factor in the development of hypertension. [7] Salt sensitivity is characterized by an increase in blood pressure with an increase in dietary salt and is associated with various genetic, demographic, and physiological factors— African American populations, postmenopausal women, and older individuals carry a higher ...
“In many people, excess dietary sodium increases blood pressure,” says Lichtenstein. “High blood pressure is associated with increased risk of stroke, heart disease, [and] age-related ...
But you could also have low-level inflammation quietly lurking in tissues and wreaking havoc in your body for years. Inflammation is complex both in the ways it can manifest and how it can be treated.
Chronic conditions increase bodily inflammation, including in the brain. Therefore, taking steps to control blood sugar, blood pressure, and weight, and making corresponding lifestyle adjustment ...
Uncontrollable increase in blood pressure can cause damage to the arteries that are present around kidneys, and thus restrict the blood to deliver. Due to inconsistent fluctuations in blood pressure, this can cause additional problems to people with pre-existing heart or blood vessel conditions such as angina, cerebral aneurysm or aortic ...
A diagram explaining factors affecting arterial pressure. Pathophysiology is a study which explains the function of the body as it relates to diseases and conditions. The pathophysiology of hypertension is an area which attempts to explain mechanistically the causes of hypertension, which is a chronic disease characterized by elevation of blood pressure.