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  2. Lactate dehydrogenase - Wikipedia

    en.wikipedia.org/wiki/Lactate_dehydrogenase

    Lactate dehydrogenase (LDH or LD) is an enzyme found in nearly all living cells. ... Many cancers can raise LDH levels, so LDH may be used as a tumor marker, but at ...

  3. Tumor marker - Wikipedia

    en.wikipedia.org/wiki/Tumor_marker

    For example, tumor markers like Ki-67 can be used to choose form of treatment or in prognostics but are not useful to give a diagnosis, while other tumor markers have the opposite functionality. Therefore it's important to follow the guidelines of the specific tumor marker. Tumor markers are mainly used in clinical medicine to support a ...

  4. Lactate dehydrogenase A - Wikipedia

    en.wikipedia.org/wiki/Lactate_dehydrogenase_A

    Lactate dehydrogenase A catalyzes the inter-conversion of pyruvate and L-lactate with concomitant inter-conversion of NADH and NAD +. LDHA is found in most somatic tissues, though predominantly in muscle tissue and tumors, and belongs to the lactate dehydrogenase family. It has long been known that many human cancers have higher LDHA levels ...

  5. Seminoma - Wikipedia

    en.wikipedia.org/wiki/Seminoma

    Lactate dehydrogenase (LDH) may be the only marker that is elevated in some seminomas. The degree of elevation in the serum LDH has prognostic value in advanced seminoma. [9] The cut surface of the tumour is fleshy and lobulated, and varies in colour from cream to tan to pink.

  6. Tumor hypoxia - Wikipedia

    en.wikipedia.org/wiki/Tumor_hypoxia

    In many different tumor types lactate dehydrogenase A is found at elevated levels and has even been linked to poor prognosis and a greater metastatic potential [24] The high levels of lactate production surface the question of whether lactate has some influence on the aggressive behaviour shown in hypoxic tumors.

  7. Mantle cell lymphoma - Wikipedia

    en.wikipedia.org/wiki/Mantle_cell_lymphoma

    Testing for high levels of lactate dehydrogenase in patients with non-Hodgkin's lymphoma is useful because it is released when body tissues break down for any reason. While it cannot be used as a sole means of diagnosing non-Hodgkin's lymphoma, it is a marker for tracking tumor burden in those diagnosed by other means.

  8. Category:Tumor markers - Wikipedia

    en.wikipedia.org/wiki/Category:Tumor_markers

    Biomarkers found in blood, urine, or body tissues that can be introduced or elevated by the presence of one or more types of cancer. Pages in category "Tumor markers" The following 45 pages are in this category, out of 45 total.

  9. Cardiac marker - Wikipedia

    en.wikipedia.org/wiki/Cardiac_marker

    Lactate dehydrogenase catalyses the conversion of pyruvate to lactate. LDH-1 isozyme is normally found in the heart muscle and LDH-2 is found predominantly in blood serum. A high LDH-1 level to LDH-2 suggest MI. LDH levels are also high in tissue breakdown or hemolysis. It can mean cancer, meningitis, encephalitis, or HIV. This is usually back ...