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User review: “I have very sensitive, acne-prone skin and it has been so hard finding a retinol that doesn’t irritate my skin,” one Amazon reviewer wrote. “This one didn’t do that ...
Tretinoin, also known as all-trans retinoic acid (ATRA), is a medication used for the treatment of acne and acute promyelocytic leukemia. [ 8 ] [ 9 ] [ 10 ] For acne, it is applied to the skin as a cream, gel or ointment. [ 10 ]
Adapalene, sold under the brand name Differin among others, is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne, and is also used off-label to treat keratosis pilaris as well as other skin conditions. [6] Studies have found adapalene is as effective as other retinoids, while causing less irritation. [7]
First generation retinoids are produced naturally in the body and interact with their normal biological counterparts, such as retinol binding protein 4 for retinol, retinoid receptors for all-trans-retinoic acid or 9-cis-retinoic acid. [9] 13-cis retinoic acid has an unknown biological pathway but appears to act as a growth factor. [10] Second ...
Retinol, also called vitamin A 1, is a fat-soluble vitamin in the vitamin A family that is found in food and used as a dietary supplement. [3] Retinol or other forms of vitamin A are needed for vision, cellular development, maintenance of skin and mucous membranes, immune function and reproductive development. [3]
Isotretinoin, also known as 13-cis-retinoic acid and sold under the brand name Accutane among others, is a medication used to treat skin diseases like harlequin-type ichthyosis, and lamellar ichthyosis, and severe cystic acne or moderate acne that is unresponsive to antibiotics. [6]