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Tetrahydrocannabinol (THC) is a cannabinoid found in cannabis. [9] It is the principal psychoactive constituent of cannabis and one of at least 113 total cannabinoids identified on the plant. Although the chemical formula for THC (C 21 H 30 O 2 ) describes multiple isomers , [ 10 ] the term THC usually refers to the delta-9-THC isomer with ...
11-Hydroxy-Δ-8-tetrahydrocannabinol (11-OH-Δ 8-THC, alternatively numbered as 7-OH-Δ 6-THC) is an active metabolite of Δ 8-THC, a psychoactive cannabinoid found in small amounts in cannabis. It is an isomer of 11-OH-Δ 9-THC, and is produced via the same metabolic pathway. It was the first cannabinoid metabolite discovered in 1970. [1]
11-Hydroxy-Δ 9-tetrahydrocannabinol (11-OH-Δ 9-THC, alternatively numbered as 7-OH-Δ 1-THC), usually referred to as 11-hydroxy-THC is the main active metabolite of tetrahydrocannabinol (THC), which is formed in the body after Δ 9-THC is consumed.
A dried cannabis flower. The short-term effects of cannabis are caused by many chemical compounds in the cannabis plant, including 113 [clarification needed] different cannabinoids, such as tetrahydrocannabinol, and 120 terpenes, [1] which allow its drug to have various psychological and physiological effects on the human body.
Δ-8-tetrahydrocannabinol (delta-8-THC, [a] Δ 8-THC) is a psychoactive cannabinoid found in the cannabis plant. [1] It is an isomer of delta-9-tetrahydrocannabinol (delta-9-THC, Δ 9 -THC), the compound commonly known as THC, with which it co-occurs in hemp ; natural quantities of ∆ 8 -THC found in hemp are low.
The cannabinoid receptor 2 (CB2), is a G protein-coupled receptor from the cannabinoid receptor family that in humans is encoded by the CNR2 gene. [5] [6] It is closely related to the cannabinoid receptor 1 (CB1), which is largely responsible for the efficacy of endocannabinoid-mediated presynaptic-inhibition, the psychoactive properties of tetrahydrocannabinol (THC), the active agent in ...
Dronabinol is the principal psychoactive constituent enantiomer form, (−)-trans-Δ 9-tetrahydrocannabinol, found in Cannabis sativa L. plants, [8] but can also be synthesized in laboratory. Dronabinol does not include any other tetrahydrocannabinol (THC) isomers or any cannabidiol.
Δ-11-Tetrahydrocannabinol (Delta-11-THC, Δ 11-THC, Δ 9(11)-THC, exo-Tetrahydrocannabinol) is a rare isomer of tetrahydrocannabinol, developed in the 1970s. It can be synthesised from Δ 8 -THC by several different routes, [ 1 ] [ 2 ] [ 3 ] though only the (6aR, 10aR) enantiomer is known.
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