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Intrauterine growth restriction (IUGR), or fetal growth restriction, is the poor growth of a fetus while in the womb during pregnancy. IUGR is defined by clinical features of malnutrition and evidence of reduced growth regardless of an infant's birth weight percentile. [ 5 ]
Intrauterine growth restriction may cause or be the result of hypoxia. Intrauterine hypoxia can cause cellular damage that occurs within the central nervous system (the brain and spinal cord). This results in an increased mortality rate, including an increased risk of sudden infant death syndrome (SIDS).
If small for gestational age babies have been the subject of intrauterine growth restriction, formerly known as intrauterine growth retardation, [5] the term "SGA associated with intrauterine growth restriction" is used. Intrauterine growth restriction refers to a condition in which a fetus is unable to achieve its genetically determined ...
Associative prevention mechanisms can be a method of minimising the risk of developing the disease, within early stages of pregnancy. Placental syndromes include pregnancy loss, fetal growth restriction, preeclampsia, preterm delivery, premature rupture of membranes, placental abruption and intrauterine fetal demise. [7]
Intrauterine growth restriction (IUGR) associated with placental insufficiency. Insufficient fetal growth can result in reduced amniotic fluid volume. When the fetus is not growing appropriately, it may have a reduced ability to produce urine, which is a significant contributor to amniotic fluid. [11]
Problems with the placenta can prevent it from providing adequate oxygen and nutrients to the fetus, resulting in growth restriction. Infections during pregnancy that affect the fetus, such as rubella, cytomegalovirus, toxoplasmosis, and syphilis, may also affect the baby's weight. [citation needed]
An impaired placenta cannot support the pregnancy and this may lead to the loss of a chromosomally normal baby. [5] On the other hand, an apparently normal diploid fetus may experience problems with growth or development due to the effects of uniparental disomy (UPD). Intrauterine growth restriction (IUGR) has been reported in a number of CPM ...
It causes reduced growth of the foetus, and leads to miscarriage in nearly 1 in 3 pregnancies affected. There are typically no symptoms, and it is rarely detected before birth. The cause is unknown, but may be autoimmune. Diagnosis is based on the histology (cell appearance) of the placenta. There are currently no known treatments.