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The main metabolite excreted in the urine is 11-Nor-9-carboxy-THC, also known as THC-COOH. Most cannabis drug tests yield a positive result when the concentration of THC-COOH in urine exceeds 50 ng/mL. [10] Urine testing is an immunoassay based test on the principle of competitive binding. Drugs which may be present in the urine specimen ...
These include tests that are intended to directly measure the function of the kidneys, as well as tests that assess the function of the kidneys by looking for evidence of problems associated with abnormal function. One of the measures of kidney function is the glomerular filtration rate (GFR). Other tests that can assess the function of the ...
Other concerns include difficulties for drug testing due to novel metabolites, or high potency/binding affinity of isomers for cannabinoid receptors showing potential for abuse (i.e., THCP, which has 33× the binding affinity of Δ 9-THC) [70] [71] From 2021 to 2023, the Δ 8-THC market generated US$2 billion in revenue. [72]
More and more states are legalizing marijuana for medical and/or recreational use. High blood pressure is a major risk factor for heart attack and stroke. Stage 1 hypertension is defined as a ...
Even eating a gummy on a full stomach can delay or prolong the effect of an edible. ... Unlike the blood alcohol limit — which is easier to define and detect with roadside tests — cannabis ...
THC and its 11-OH-THC and THC-COOH metabolites can be detected and quantified in blood, urine, hair, oral fluid or sweat using a combination of immunoassay and chromatographic techniques as part of a drug use testing program or in a forensic investigation. [57] [58] [59] There is ongoing research to create devices capable of detecting THC in ...