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Degenerative disc disease; Other names: Degenerative disc disorder, intervertebral disc degeneration: Degenerated disc between C5 and C6 (vertebra at the top of the picture is C2), with osteophytes anteriorly (to the left) on the lower portion of the C5 and upper portion of the C6 vertebral body.
Some authors favour degeneration of the intervertebral disc as the major cause of spinal disc herniation and cite trauma as a minor cause. [7] Disc degeneration occurs both in degenerative disc disease and aging. [8] With degeneration, the disc components – the nucleus pulposus and annulus fibrosus – become exposed to altered loads ...
Degenerative process of spondylosis such as disc bulging, osteophyte formation, and hypertrophy of the superior articular process all contributes to the narrowing of the spinal canal and intervertebral foramen, leading to compression of these spinal nerves that results in radiculopathy-related symptoms.
The condition is likely triggered by changes in the anulus fibrosus, the tough outer ring of the intervertebral disc. This disc degeneration causes osteophytes to grow in the area. The osteophytes develop bridges of connective tissue which become ossified, forming bone spurs. The pattern of osteophyte formation varies.
Intervertebral discs may bulge or herniate into the canal or foraminal openings [26] Degenerative disc disease causes narrowing of the spaces. [27] Facet joints break down; Facet joints may hypertrophy [28] Compression fractures of the spine, which are common in osteoporosis [29]
Schmorl's nodes are fairly common, especially with minor degeneration of the aging spine, but they are also seen in younger spines. Schmorl's nodes often cause no symptoms, but may simply reflect that "wear and tear" of the spine has occurred over time; they may also reflect that bone strength was at one time somewhat compromised, perhaps due to a vitamin D deficiency although this has yet to ...
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