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14415 Ensembl ENSG00000128683 ENSMUSG00000070880 UniProt Q99259 P48318 RefSeq (mRNA) NM_000817 NM_013445 NM_008077 NM_001312900 RefSeq (protein) NP_000808 NP_038473 NP_001299829 NP_032103 Location (UCSC) Chr 2: 170.81 – 170.86 Mb Chr 2: 70.38 – 70.43 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Glutamate decarboxylase 1 (brain, 67kDa) (GAD67), also known as GAD1, is a human ...
[29] [30] [31] In clinical trials, injections with GAD 65 have been shown to preserve some insulin production for 30 months in humans with type 1 diabetes. [32] [33] A Cochrane systematic review also examined 1 study showing improvement of C-peptide levels in cases of Latent Autoimmune Diabetes in adults, 5 years following treatment with GAD 65 ...
Various hereditary conditions may feature diabetes, for example myotonic dystrophy and Friedreich's ataxia. Wolfram's syndrome is an autosomal recessive neurodegenerative disorder that first becomes evident in childhood. It consists of diabetes insipidus, diabetes mellitus, optic atrophy, and deafness, hence the acronym DIDMOAD. [20]
Detoxification (often shortened to detox and sometimes called body cleansing) is a type of alternative-medicine treatment which aims to rid the body of unspecified "toxins" – substances that proponents claim accumulate in the body over time and have undesirable short-term or long-term effects on individual health.
deCODE genetics (Icelandic: Íslensk erfðagreining) is a biopharmaceutical company based in Reykjavík, Iceland.The company was founded in 1996 by Kári Stefánsson [1] with the aim of using population genetics studies to identify variations in the human genome associated with common diseases, and to apply these discoveries "to develop novel methods to identify, treat and prevent diseases."
The domain structure of GLUD1 Each domain is colored differently - Glu-BD, NAD(P)-BD, antenna, the pivot helix.The allosteric regulators are shown as sphere models. This particular structure of GLUD1 is a combination of two X-ray structures - one with a bound GTP and the second one with a bound ADP (1NQT,8AR8).