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The research combined diverse techniques ranging from genomics, computational biology, tumour imaging, in vitro and in vivo functional models to study biological and clinical phenotypes. The proteins produced by these genes may serve as targets for novel chemotherapy drugs and other cancer treatments, or imaging scans.
The journal covers developments in "medicinal chemistry and rational drug design for the discovery of anti-cancer agents" and publishes original research reports and review papers. [1] It is related to the journal Current Medicinal Chemistry and was established in 2001 as Current Medicinal Chemistry – Anti-Cancer Agents. [2]
There can be many years between promising laboratory work and the availability of an effective anti-cancer drug: Monroe Eliot Wall discovered anti-cancer properties in Camptotheca in 1958, but it was not until 1996 – after further research and rounds of clinical trials – that topotecan, a synthetic derivative of a chemical in the plant, was ...
The institution was originally established under the name NCI-Frederick Cancer Research Center in 1972 as a component of U.S. President Richard Nixon's War on Cancer initiative. In 2012, the institution received a National Laboratory designation and assumed its current name, becoming the only U.S. national laboratory dedicated entirely to ...
Anticancer Research was established in 1981 by John G. Delinassios. According to the Journal Citation Reports, the journal had a 2020 impact factor of 2.480 and 25,656 total cites. The 2020 rejection rate was 68%. According to Scimago, the journal belongs to the second quartile (Q2) in the "Medicine" category.
Current ongoing research by the Mayo Clinic laboratories includes the examination of AuNPs as messengers to deliver reagents capable of manipulating the angiogenic response in vivo. [ 18 ] Current angiogenic inhibitors used today which are approved by the USFDA to treat cancer is Ayastin, Nexavar , Sutent and Affinitor.
It covers research on all aspects of cancer and cancer-related biomedical sciences and was established in 1941. The editor-in-chief is Chi Van Dang. [1] The journal was established in 1916 as the Journal of Cancer Research, was renamed American Journal of Cancer in 1931, and obtained its current name in 1941.
Antacids and chelating agents combine chemically in the body. Enzyme-substrate binding is a way to alter the production or metabolism of key endogenous chemicals, for example aspirin irreversibly inhibits the enzyme prostaglandin synthetase (cyclooxygenase) thereby preventing inflammatory response.