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The TATA box has a binding site for the transcription factor of the PG2 gene. This gene produces PG2 serum, which is used as a biomarker for tumours in gastric cancer. Longer TATA box sequences correlates with higher levels of PG2 serum indicating gastric cancer conditions. Carriers with shorter TATA box sequences may produce lower levels of ...
There is a highly conserved 130-nt region just downstream of the TATA box. [3] ... plasma/serum, PBMCs, bone marrow, spleen, pancreas, kidneys, nervous tissue, lymph ...
The TATA-binding protein (TBP) is a general transcription factor that binds to a DNA sequence called the TATA box. This DNA sequence is found about 30 base pairs upstream of the transcription start site in some eukaryotic gene promoters .
However, Gilbert syndrome can arise without TATA box promoter polymorphic variants; in some populations, particularly healthy Southeast and East Asians, Gilbert's syndrome is more often a consequence of heterozygote missense mutations (such as Gly71Arg also known as UGT1A1*6, Tyr486Asp also known as UGT1A1*7, Pro364Leu also known as UGT1A1*73 ...
The B recognition element (BRE) is a DNA sequence found in the promoter region of most [clarification needed] genes in eukaryotes and Archaea. [1] [2] The BRE is a cis-regulatory element that is found immediately near TATA box, and consists of 7 nucleotides.
A common basal promoter is the TATAAAAAA sequence known as the TATA box. The TATA box is a complex with several different proteins including transcription factor II D (TFIID) which includes the TATA-binding protein (TBP) that binds to the TATA box along with 13 other proteins that bind to TBP. The TATA box binding proteins also include the ...