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Most glycosyltransferase enzymes form one of two folds: GT-A or GT-B. Glycosyltransferases (GTFs, Gtfs) are enzymes that establish natural glycosidic linkages.They catalyze the transfer of saccharide moieties from an activated nucleotide sugar (also known as the "glycosyl donor") to a nucleophilic glycosyl acceptor molecule, the nucleophile of which can be oxygen- carbon-, nitrogen-, or sulfur ...
Histo-blood group ABO system transferase is an enzyme with glycosyltransferase activity, which is encoded by the ABO gene in humans. [5] [6] It is ubiquitously expressed in many tissues and cell types. [7] ABO determines the ABO blood group of an individual by modifying the oligosaccharides on cell surface glycoproteins. Variations in the ...
Glycosyltransferase is a subcategory of EC 2.4 transferases that is involved in biosynthesis of disaccharides and polysaccharides through transfer of monosaccharides to other molecules. [40] An example of a prominent glycosyltransferase is lactose synthase which is a dimer possessing two protein subunits .
Glucosyltransferases are a type of glycosyltransferase that enable the transfer of glucose. [1] Examples include: glycogen synthase; glycogen phosphorylase; They are categorized under EC number 2.4.1.
Other names in common use include oligoglucan-branching glycosyltransferase, 1,4-alpha-D-glucan 6-alpha-D-glucosyltransferase, T-enzyme, and D-glucosyltransferase.
In secretors, α-2-L-fucosyltransferase modifies this precursor substance, which causes it to form Le(b) when acted on by the enzyme encoded by the Le gene. Thus, secretors who are positive for Le express the Le(a-b+) type, while non-secretors who are positive for Le express the Le(a+b-) blood type. [note 2] [1]: 178–81 [3]: 196
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