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The effects of rosuvastatin on low-density lipoprotein (LDL) cholesterol are dose-related. Higher doses were more efficacious in improving the lipid profile of patients with hypercholesterolemia than milligram-equivalent doses of atorvastatin and milligram-equivalent or higher doses of simvastatin and pravastatin.
Use during pregnancy may harm the baby and use during breastfeeding is not recommended. [3] It works by decreasing the liver's ability to produce cholesterol by blocking the enzyme HMG-CoA reductase. [2] Lovastatin was patented in 1979 and approved for medical use in 1987. [4] It is on the World Health Organization's List of Essential Medicines ...
Statins (or HMG-CoA reductase inhibitors) ... The class is on the World Health Organization's List of Essential Medicines with simvastatin being the listed medicine. [10]
A 2010 published meta-analysis found for every 255 patients taking a statin for 4 years, one additional case of diabetes would occur whilst preventing 5.4 major coronary events. [27] Some drugs interact with statins in a way that increases the risk of muscle injury called myopathy, characterized by unexplained muscle weakness or pain.
Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in the liver that plays a role in producing cholesterol. [6] Atorvastatin was patented in 1986, and approved for medical use in the United States in 1996. [6] [7] It is on the World Health Organization's List of Essential Medicines. [8]
Cholesterol: Population-wide health education through mass media Individual-based treatment and education: In all subregions, population strategies to reduce cholesterol are very cost-effective, but the total impact on DALYs gained is small. Statins are low-cost and effective and thus cost-effective in all regions.
FD&C Red No. 40, more commonly known as red 40, is making headlines again as lawmakers debate whether food dyes should remain legal in the United States.. The dye, which has been registered with ...
Breastfeeding and medications is the description of the medications that can be used by a breastfeeding mother, and the balance between maternal health and the safety of the breastfeeding infant. [1] [2] Medications, when administered to breastfeeding mothers, almost always are transferred to breast milk, albeit usually in small quantities. [3]