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Buspirone can be useful in GAD but not particularly effective in treating phobias, panic disorder or social anxiety disorders. [2] It is a safer option for long-term use as it does not cause dependence like benzodiazepines.
Buspirone, sold under the brand name Buspar among others, is an anxiolytic, a medication primarily used to treat anxiety disorders, particularly generalized anxiety disorder (GAD). [ 10 ] [ 11 ] It is a serotonin 5-HT 1A receptor partial agonist , increasing action at serotonin receptors in the brain. [ 3 ]
Inderal (propranolol) – a beta blocker; it is used for acute anxiety, panic attacks, and hypertension; Intuniv - an extended release, non-stimulant alpha-2 adrenergic agonist used to treat attention deficit hyperactivity disorder. Available in instant-release under the brand-name Tenex.
Propranolol was patented in 1962 and approved for medical use in 1964. [9] It is on the World Health Organization's List of Essential Medicines. [10] Propranolol is available as a generic medication. [2] In 2022, it was the 77th most commonly prescribed medication in the United States, with more than 8 million prescriptions. [11] [12]
Key symptoms include excessive anxiety about multiple events and issues, and difficulty controlling worrisome thoughts, that persists for at least 6 months. Antidepressants provide a modest-to-moderate reduction in anxiety in GAD, [25] and are superior to placebo in treating GAD. The efficacy of different antidepressants is similar.
5-HT 1A receptor agonists like buspirone [18] and flesinoxan [19] show efficacy in relieving anxiety [20] and depression. [21] Buspirone and tandospirone are currently approved for these indications in different parts of the world.
This is a list of psychiatric medications used by psychiatrists and other physicians to treat mental illness or distress.. The list is ordered alphabetically according to the condition or conditions, then by the generic name of each medication.
Azapirones have shown benefit in general anxiety [14] and augmenting SSRIs in social anxiety [15] and depression. [16] Evidence is not clear for panic disorder [17] and functional gastrointestinal disorders. [18] Tandospirone has also been used to augment antipsychotics in Japan as it improves cognitive and negative symptoms of schizophrenia. [19]