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Only the Orc1-5 subunits are required for origin binding; Orc6 is essential for maintenance of pre-RCs once formed. [24] Interactions within ORC suggest that Orc2-3-6 may form a core complex. [4] A 2020 report suggests that budding yeast ORC dimerizes in a cell cycle dependent manner to control licensing. [25] [26]
The ORCID (/ ˈ ɔːr k ɪ d / ⓘ; Open Researcher and Contributor ID) is a nonproprietary alphanumeric code to uniquely identify authors and contributors of scholarly communication [1] as well as ORCID's website and services to look up authors and their bibliographic output (and other user-supplied pieces of information).
The protein encoded by this gene is a subunit of the ORC complex. It has been shown that this protein and ORC1 are loosely associated with the core complex consisting of ORC2 , -3 , -4 and -5 . Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and ...
Clinical trial registration is the practice of documenting clinical trials before they are performed in a clinical trials registry so as to combat publication bias and selective reporting. [25] Registration of clinical trials is required in some countries and is increasingly being standardized. [ 26 ]
ORC Rating Officers. The 'Central Rating Office' establishes delegated Rating Offices [5] in each country with active offshore racing. Rating offices issue ORC International and ORC Club certificates and administer their national fleets [6] by supervising the measurement and rating of the yachts. For countries where a national Rating Office is ...
A pre-replication complex (pre-RC) is a protein complex that forms at the origin of replication during the initiation step of DNA replication. Formation of the pre-RC is required for DNA replication to occur. Complete and faithful replication of the genome ensures that each daughter cell will carry the same genetic information as the parent cell.
T-s diagram for the ideal/real ORC. The working principle of the organic Rankine cycle is the same as that of the Rankine cycle: the working fluid is pumped to a boiler where it is evaporated, passed through an expansion device (turbine, [3] screw, [4] scroll, [5] or other expander), and then through a condenser heat exchanger where it is finally re-condensed.
Ohio Revised Code, statutes of the U.S. state of Ohio; Opinion Research Corporation, a polling and market research company; O.R.C., postnominal letters for members of the Canons Regular of the Holy Cross of Coimbra; Order of Railway Conductors, an American trade union; Organic Rankine Cycle; Organized retail crime; Origin recognition complex, a ...