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Nickel–methyl intermediates have been proposed for the final step of methanogenesis. Methylcobalamin is equivalent physiologically to vitamin B 12, [3] [non-primary source needed] and can be used to prevent or treat pathology arising from a lack of vitamin B 12 intake (vitamin B 12 deficiency). [medical citation needed] [dubious – discuss]
Pernicious anemia is the most common cause of vitamin B 12 deficiency anemia in adults, which results from malabsorption of vitamin B 12 due to a lack or loss of intrinsic factor. [2] [8] There are relatively few studies which have assessed the impact of haematological measures in response to B 12 supplementation.
[6] [15] [26] Vitamin B 12 deficiency can also cause symptoms of mania and psychosis. [27] [28] Among other problems, weakened immunity, reduced fertility and interruption of blood circulation in women may occur. [29] The main type of vitamin B12 deficiency anemia is pernicious anemia, [30] characterized by a triad of symptoms:
Methyl B Complex. Loaded with B2, B6, B12 and folate, ... Your body can end up making fewer red blood cells if you have a vitamin B12 deficiency, leading to a specific type of anemia, ...
Lack of vitamin B12 can cause megaloblastic anemia—a condition characterized by larger than normal red blood cells in a smaller than normal amount. This causes fatigue, paleness in the skin ...
Pernicious anemia is the most common cause of clinically evident vitamin B 12 deficiency worldwide. [14] Pernicious anemia due to autoimmune problems occurs in about one per 1000 people in the US. Among those over the age of 60, about 2% have the condition. [ 8 ]