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  2. Partial thromboplastin time - Wikipedia

    en.wikipedia.org/wiki/Partial_thromboplastin_time

    The partial thromboplastin time (PTT), also known as the activated partial thromboplastin time (aPTT or APTT), is a blood test that characterizes coagulation of the blood.A historical name for this measure is the Kaolin-cephalin clotting time (KCCT), [1] reflecting kaolin and cephalin as materials historically used in the test.

  3. Activated clotting time - Wikipedia

    en.wikipedia.org/wiki/Activated_clotting_time

    Activated clotting time (ACT), also known as activated coagulation time, is a test of coagulation. [1] [2]The ACT test can be used to monitor anticoagulation effects, such as from high-dose heparin before, during, and shortly after procedures that require intense anticoagulant administration, such as cardiac bypass, interventional cardiology, thrombolysis, extra-corporeal membrane oxygenation ...

  4. Clotting time - Wikipedia

    en.wikipedia.org/wiki/Clotting_time

    Clotting time is a general term for the time required for a sample of blood to form a clot, or, in medical terms, coagulate. The term "clotting time" is often used when referring to tests such as the prothrombin time (PT) , activated partial thromboplastin time (aPTT or PTT), activated clotting time (ACT), thrombin time (TT), or Reptilase time .

  5. Thromboplastin - Wikipedia

    en.wikipedia.org/wiki/Thromboplastin

    Partial thromboplastin was used to measure the intrinsic pathway. This test is called the aPTT, or activated partial thromboplastin time. It was not until much later that the subcomponents of thromboplastin and partial thromboplastin were identified. Thromboplastin is the combination of both phospholipids and tissue factor, both of which are ...

  6. Coagulation - Wikipedia

    en.wikipedia.org/wiki/Coagulation

    The contact activation (intrinsic) pathway is initiated by activation of the contact activation system, and can be measured by the activated partial thromboplastin time (aPTT) test. [ 48 ] The tissue factor (extrinsic) pathway is initiated by release of tissue factor (a specific cellular lipoprotein), and can be measured by the prothrombin time ...

  7. Tissue factor - Wikipedia

    en.wikipedia.org/wiki/Tissue_factor

    Historically, thromboplastin was a lab reagent, usually derived from placental sources, used to assay prothrombin times (PT time). Thromboplastin, by itself, could activate the extrinsic coagulation pathway. When manipulated in the laboratory, a derivative could be created called partial thromboplastin, which was used to measure the intrinsic ...

  8. Coagulation testing - Wikipedia

    en.wikipedia.org/wiki/Coagulation_testing

    Activated partial thromboplastin time (APTT or aPTT) Characteristics of the velocity of passage of the intrinsic coagulation pathway; Poor plasma (the most convenient to work with, but no realization of the thrombocyte clotting mechanism) Contact activation pathway

  9. Factor XII - Wikipedia

    en.wikipedia.org/wiki/Factor_XII

    2161 58992 Ensembl ENSG00000131187 ENSMUSG00000021492 UniProt P00748 Q80YC5 RefSeq (mRNA) NM_000505 NM_021489 RefSeq (protein) NP_000496 NP_067464 Location (UCSC) Chr 5: 177.4 – 177.42 Mb Chr 13: 55.57 – 55.57 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Coagulation factor XII, also known as Hageman factor, is a plasma protein involved in coagulation. It is the zymogen form of ...