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Sepsis was the most expensive condition treated in United States' hospital stays in 2013, at an aggregate cost of $23.6 billion for nearly 1.3 million hospitalizations. [132] Costs for sepsis hospital stays more than quadrupled since 1997 with an 11.5 percent annual increase. [133]
Millions are affected by sepsis each year, with a rate of 0.2-3 people per thousand, per year in the developed world [10] [11]. But the global burden of disease is unknown since little data exists from the developing world [ 10 ] .
"Sepsis is an overwhelming body reaction for any infection and sepsis is a life-threatening condition," Rangaswamy said. "If not diagnosed early and not treated, it can cause significant mortality ...
Sepsis can cause a drop in body temperature and severe shivering, which is one of a response to fighting infection, and is the body’s way of trying to increase its temperature.
Both SIRS and sepsis could ultimately progress to multiple organ dysfunction syndrome. In one-third of the patients, however, no primary focus can be found. [1] Multiple organ dysfunction syndrome is well established as the final stage of a continuum: SIRS + infection → sepsis → severe sepsis → Multiple organ dysfunction syndrome.
An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. [1] An infectious disease, also known as a transmissible disease or communicable disease, is an illness resulting from an infection.
Original file (WebM audio/video file, VP9/Opus, length 4 min 5 s, 1,280 × 720 pixels, 396 kbps overall, file size: 11.55 MB) This is a file from the Wikimedia Commons . Information from its description page there is shown below.
Meningococcal disease causes life-threatening meningitis and sepsis conditions. In the case of meningitis, bacteria attack the lining between the brain and skull called the meninges. Infected fluid from the meninges then passes into the spinal cord, causing symptoms including stiff neck, fever and rashes.