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The signs and symptoms of oral cancer depend on the location of the tumor but are generally thin, irregular, red and/or white patches in the mouth. The classic warning sign is a persistent rough patch with ulceration , and a raised border that is minimally painful.
Oropharyngeal cancer, [1] [2] [3] also known as oropharyngeal squamous cell carcinoma and tonsil cancer, [1] is a disease in which abnormal cells with the potential to both grow locally and spread to other parts of the body are found in the oral cavity, in the tissue of the part of the throat that includes the base of the tongue, the tonsils, the soft palate, and the walls of the pharynx.
Cases have risen dramatically over last decade, according to recent research
In those with advanced disease, there may be unusual bleeding, facial pain, numbness or swelling, and visible lumps on the outside of the neck or oral cavity. [15] Head and neck cancer often begins with benign signs and symptoms of the disease, like an enlarged lymph node on the outside of the neck, a hoarse-sounding voice, or a progressive ...
HPV+OPC presents in one of four ways: as an asymptomatic abnormality in the mouth found by the patient or a health professional such as a dentist; with local symptoms such as pain or infection at the site of the tumor; with difficulties of speech, swallowing, and/or breathing; or as a swelling in the neck (if the cancer has spread to lymph nodes).
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This wound-like ulcer fails to heal (non-healing) leading to bleeding and throat pain and other associated symptoms. [citation needed] During biopsy, the lesion may show three signs: gritty texture, firmness and cystification owing to keratinization, fibrosis and necrosis respectively. [8] Cervical lymphadenopathy may be present. [citation needed]
Oral leukoplakia is a gray patch or plaque that develops in the oral cavity and is strongly associated with smoking. [8] Leukoplakia is a firmly attached white patch on a mucous membrane which is associated with increased risk of cancer. [4] [5] The edges of the lesion are typically abrupt and the lesion changes with time.