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It has also been defined as increased amount of saliva in the mouth, which may also be caused by decreased clearance of saliva. [ 4 ] Hypersalivation can contribute to drooling if there is an inability to keep the mouth closed or difficulty in swallowing (dysphagia) the excess saliva, which can lead to excessive spitting.
Pyridoxine/doxylamine, sold under the brand name Diclectin among others, is a combination of pyridoxine hydrochloride (vitamin B 6) and doxylamine succinate.It is generally used for nausea and vomiting of pregnancy (morning sickness); even though its efficacy has not been proven and subsequent research has led to the removal of recommendations in medical journals.
Known side effects include nausea, vomiting, diarrhea, excessive sweating, rash, headache, runny nose, cough, drowsiness, hot flashes, blurred vision, and difficulty sleeping. [3] Contraindications include asthma and angle closure glaucoma. [citation needed]
Antihistamines may be prescribed in early pregnancy for the treatment of nausea and vomiting along with symptoms of asthma and allergies. [54] First generation antihistamines include diphenhydramine (Benadryl), chlorpheniramine (Diabetic Tussin), hydroxyzine (Atarax), and doxepin (Sinequan). [55]
Scopolamine, also known as hyoscine, [9] or Devil's Breath, [10] is a natural or synthetically produced tropane alkaloid and anticholinergic drug that is used as a medication to treat motion sickness [11] and postoperative nausea and vomiting. [12] [1] It is also sometimes used before surgery to decrease saliva. [1]
Preliminary clinical data suggests ginger may be effective for treatment of nausea and/or vomiting in a number of settings. [20] [21] [22] Emetrol is also claimed to be an effective antiemetic. Propofol is given intravenously. It has been used in an acute care setting in hospital as a rescue therapy for emesis. [23]
Huperzine A may present with mild cholinergic side effects such as nausea, vomiting, and diarrhea. [5] Slight muscle twitching and slurred speech might also occur, as well as excessive saliva excretion and sweating. The use of huperzine A during pregnancy and lactation is not recommended due to the lack of sufficient safety data. [17]
Common side effects include vomiting, diarrhea, rash, and increased liver enzymes. [5] Serious side effects may include liver problems, QT prolongation, and seizures. [5] During pregnancy it may increase the risk of miscarriage while large doses may cause birth defects. [6] [5] Fluconazole is in the azole antifungal family of medication. [5]