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Combination use of two medications are available as nasal sprays. List of some combination nasal sprays: Azelastine together with fluticasone propionate (brand names including Dymista) [4] Xylometazoline together with cromoglicic acid; In some countries, Dymista is marketed by Viatris after Upjohn merged with Mylan to create Viatris. [6] [7]
Treatment can be given as an injection, tablet, sprays or sublingual drops. The gradual increase of allergen causes the immune system to become less sensitive to the substance ( desensitization ), reducing symptoms during future exposures to the allergen, and possibly preventing new allergies.
Azelastine, sold under the brand name Astelin among others, is a H 1 receptor-blocking medication primarily used as a nasal spray to treat allergic rhinitis (hay fever) and as eye drops for allergic conjunctivitis. [5] [6] Other uses may include asthma and skin rashes for which it is taken by mouth. [7]
Fluticasone propionate, sold under the brand names Flovent and Flonase among others, is a glucocorticoid steroid medication. [8] When inhaled it is used for the long term management of asthma and COPD. [8] In the nose it is used for hay fever and nasal polyps. [9] [10] It can also be used for mouth ulcers. [11] It works by decreasing inflammation.
Fluticasone furoate is indicated for the treatment of the symptoms of allergic rhinitis, [8] and asthma. [6] [7] Fluticasone Furoate is a corticosteroid medication primarily used to treat allergic rhinitis (hay fever) and non-allergic (perennial) rhinitis. It is also indicated for the treatment of nasal polyps in adults.
Fluticasone is a manufactured glucocorticoid used to treat nasal congestion. [1] [2] [3] [4] [5] Both the esters, fluticasone propionate (sold as Flovent) and ...
Ophthalmic antihistamines (such as azelastine in eye drop form and ketotifen) are used for conjunctivitis, while intranasal forms are used mainly for sneezing, rhinorrhea, and nasal pruritus. [52] Antihistamine drugs can have undesirable side-effects, the most notable one being drowsiness in the case of oral antihistamine tablets.
Acute use (1–3 days) yields a potency about 1.5× stronger than that of morphine and chronic use (7 days+) yields a potency about 2.5 to 5× that of morphine. Similarly, the effect of tramadol increases after consecutive dosing due to the accumulation of its active metabolite and an increase of the oral bioavailability in chronic use.