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Doxylamine is used in the combination drug pyridoxine/doxylamine to treat morning sickness (nausea and vomiting of pregnancy). [19] [20] [21] It is the only medication approved by the United States Food and Drug Administration for the treatment of morning sickness. [19] [20]
Pyridoxine/doxylamine, sold under the brand name Diclectin among others, is a combination of pyridoxine hydrochloride (vitamin B 6) and doxylamine succinate.It is generally used for nausea and vomiting of pregnancy (morning sickness); even though its efficacy has not been proven and subsequent research has led to the removal of recommendations in medical journals.
Despite its relatively short half-life, the drug is reported to remain effective for motion sickness for 12 - 24 hours. [23] Meclizine has low bioavailability (22–32%) and a delayed onset to action in part due to its poor solubility in water (0.1 mg/ml) and gastrointestinal fluid. [ 1 ]
Lorazepam (Ativan) is said to be very good as an adjunct treatment for nausea along with first line medications such as Compazine. [citation needed] Anticholinergics. Hyoscine (also known as scopolamine) Atropine; Steroids. Dexamethasone (Decadron) is given in low dose at the onset of a general anesthetic as an effective antiemetic.
Ondansetron, sold under the brand name Zofran among others, is a medication used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, migraines, or surgery. [8] It is also effective for treating gastroenteritis .
Most motion sickness medications work best when you take them 20-40 minutes before you start traveling, so make sure to plan ahead, says Malka. Avoid taking motion sickness medicines after the ...