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The ability of the immune system to recognize molecules that are broadly shared by pathogens is, in part, due to the presence of immune receptors called toll-like receptors (TLRs) that are expressed on the membranes of leukocytes including dendritic cells, macrophages, natural killer cells, cells of the adaptive immunity T cells, and B cells, and non-immune cells (epithelial and endothelial ...
Toll-like receptor 1 (TLR1) is a member of the toll-like receptor (TLR) family of pattern recognition receptors (PRRs) that form the cornerstone of the innate immune system. [5] [6] [7] TLR1 recognizes bacterial lipoproteins and glycolipids in complex with TLR2. TLR1 is a cell surface receptor. [5]
Toll-like receptor 2 also known as TLR2 is a protein that in humans is encoded by the TLR2 gene. [5] TLR2 has also been designated as CD282 ( cluster of differentiation 282). TLR2 is one of the toll-like receptors and plays a role in the immune system .
Toll-like receptor 10 is a protein that in humans is encoded by the TLR10 gene. [3] TLR10 has also been designated as CD290 ( cluster of differentiation 290). TLR10 has not been extensively studied because it is a pseudogene in mice, though all other mammalian species contain an intact copy of the TLR10 gene.
Toll-like receptor 6 is a protein that in humans is encoded by the TLR6 gene. [5] TLR6 is a transmembrane protein, member of toll-like receptor family, which belongs to the pattern recognition receptor (PRR) family. TLR6 acts in a heterodimer form with toll-like receptor 2 (TLR2).
7100 53791 Ensembl ENSG00000187554 ENSMUSG00000079164 UniProt O60602 Q9JLF7 RefSeq (mRNA) NM_003268 NM_016928 RefSeq (protein) NP_003259 NP_058624 Location (UCSC) Chr 1: 223.11 – 223.14 Mb Chr 1: 182.78 – 182.8 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Toll-like receptor 5, also known as TLR5, is a protein which in humans is encoded by the TLR5 gene. It is a member of the ...
Toll-like receptor 3 (TLR3) also known as CD283 (cluster of differentiation 283) is a protein that in humans is encoded by the TLR3 gene. [5] TLR3 is a member of the toll-like receptor family of pattern recognition receptors of the innate immune system .
Toll-like receptor 11 (TLR11) is a protein that in mice and rats is encoded by the gene TLR11, whereas in humans it is represented by a pseudogene.TLR11 belongs to the toll-like receptor (TLR) family and the interleukin-1 receptor/toll-like receptor superfamily.