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  2. Human skin - Wikipedia

    en.wikipedia.org/wiki/Human_skin

    Human skin pigmentation varies substantially between populations; this has led to the classification of people(s) on the basis of skin colour. [ 3 ] In terms of surface area, the skin is the second largest organ in the human body (the inside of the small intestine is 15 to 20 times larger).

  3. Epidermis - Wikipedia

    en.wikipedia.org/wiki/Epidermis

    The epidermis is the outermost of the three layers that comprise the skin, the inner layers being the dermis and hypodermis. [1] The epidermal layer provides a barrier to infection from environmental pathogens [2] and regulates the amount of water released from the body into the atmosphere through transepidermal water loss.

  4. Human skin color - Wikipedia

    en.wikipedia.org/wiki/Human_skin_color

    This is an accepted version of this page This is the latest accepted revision, reviewed on 22 January 2025. "Skin pigmentation" redirects here. For animal skin pigmentation, see Biological pigment. Extended Coloured family from South Africa showing some spectrum of human skin coloration Human skin color ranges from the darkest brown to the lightest hues. Differences in skin color among ...

  5. Melanin - Wikipedia

    en.wikipedia.org/wiki/Melanin

    Total melanin content in the epidermis ranges from around 0 μg/mg in albino epidermal tissue [8] to >10 μg/mg in darker tissue. [9] In the human skin, melanogenesis is initiated by exposure to UV radiation, causing the skin to darken. Eumelanin is an effective absorbent of light; the pigment is able to dissipate over 99.9% of absorbed UV ...

  6. Dermoepidermal junction - Wikipedia

    en.wikipedia.org/wiki/Dermoepidermal_junction

    H&E stained section of human skin. The dermoepidermal junction or dermal-epidermal junction (DEJ) is the interface between the epidermal and the dermal layers of the skin. The basal cells of the epidermis connect to the basement membrane by the anchoring filaments of hemidesmosomes; the cells of the papillary layer of the dermis are attached to the basement membrane by anchoring fibrils, which ...

  7. Melanocyte - Wikipedia

    en.wikipedia.org/wiki/Melanocyte

    Melanin is a dark pigment primarily responsible for skin color. Once synthesized, melanin is contained in special organelles called melanosomes which can be transported to nearby keratinocytes to induce pigmentation. Thus darker skin tones have more melanosomes present than lighter skin tones.

  8. Stratum basale - Wikipedia

    en.wikipedia.org/wiki/Stratum_basale

    Histologic image showing a section of epidermis. Stratum basale labeled near bottom.. The stratum basale (basal layer, sometimes referred to as stratum germinativum) is the deepest layer of the five layers of the epidermis, the external covering of skin in mammals.

  9. Keratinocyte - Wikipedia

    en.wikipedia.org/wiki/Keratinocyte

    In humans, they constitute 90% of epidermal skin cells. [1] Basal cells in the basal layer ( stratum basale ) of the skin are sometimes referred to as basal keratinocytes . [ 2 ] Keratinocytes form a barrier against environmental damage by heat , UV radiation , water loss , pathogenic bacteria , fungi , parasites , and viruses .