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It is an organophosphate oxon, and the active metabolite of the insecticide parathion. It is also used as an ophthalmological drug against glaucoma . Paraoxon is one of the most potent acetylcholinesterase-inhibiting insecticides available, around 70% as potent as the nerve agent sarin , and so is now rarely used as an insecticide due to the ...
Parathion, also called parathion-ethyl or diethyl parathion, is an organophosphate insecticide and acaricide.It was originally developed by IG Farben in the 1940s. It is highly toxic to non-target organisms, including humans, so its use has been banned or restricted in most countries.
It was proposed that, in order to avoid damage to the DNA genome of the oocytes, the metabolism contributing to the synthesis of much of the oocyte's constituents was shifted to other maternal cells that then transferred these constituents to oocytes. [7] [8] Thus, oocytes of many organisms are protected from oxidative DNA damage while storing ...
In other words, primary oocytes reach their maximum development at ~20 weeks of gestational age, when approximately seven million primary oocytes have been created; however, at birth, this number has already been reduced to approximately 1-2 million per ovary. At puberty, the number of oocytes decreases even more to reach about 60,000 to 80,000 ...
Approximately 1–2% of ovulations release more than one oocyte. This tendency increases with maternal age. Fertilization of two different oocytes by two different spermatozoa results in fraternal twins. [10] The precise moment of ovulation was captured on film for the first time in 2008, coincidentally, during a routine hysterectomy procedure.
Therefore, the presence of gametocytes in circulation of infected individuals is imperative for malaria to remain endemic in a given community. [ citation needed ] Male and female gametocytes are the components of the malaria parasite life cycle which are taken up from an infected host bloodstream by mosquitoes and thus mediate disease ...
Time course of drug plasma concentrations over 96 hours following oral administrations every 24 hours (τ). Absorption half-life 1 h, elimination half-life 12 h. Biological half-life ( elimination half-life , pharmacological half-life ) is the time taken for concentration of a biological substance (such as a medication ) to decrease from its ...
Emilia Bacco, 58-year-old Italian woman from Salerno, Italy, gave birth to twin boys in 1995, after IVF treatment with oocytes donation fertilized by her husband's sperm. [104] 58 years June 2001 "Pragna" India "Pragna", a 58-year-old Indian woman, from Mumbai, Maharashtra, gave birth to a son, by Caesarean section, in June 2001. [105] 58 years