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Eosinophilic gastroenteritis (EG or EGE), also known as eosinophilic enteritis, [1] is a rare and heterogeneous condition characterized by patchy or diffuse eosinophilic infiltration of gastrointestinal (GI) tissue, first described by Kaijser in 1937.
GSE has key symptoms typically restricted to the bowel and associated tissues; however, there are a wide variety of associated conditions. These include bowel disorders (diarrhoea, constipation, irritable bowel), eosinophilic gastroenteritis and increase with coeliac disease (CD) severity.
For treating eosinophilic gastroenteritis, the main treatment is usually a corticosteroid medication, as these have been shown to have good efficacy in managing eosinophilic gastroenteritis. Other treatments include modifying diets to avoid food allergies, azathioprine and antibodies, including mepolizumab , omalizumab , infliximab , and ...
Eosinophilia is a condition in which the eosinophil count in the peripheral blood exceeds 5 × 10 8 /L (500/μL). [1] Hypereosinophilia is an elevation in an individual's circulating blood eosinophil count above 1.5 × 10 9 /L (i.e. 1,500/μL).
Eosinophilic gastroenteritis: Possibly a hypersensitivity. Eosinophilic pneumonia: A class of diseases, some of which may be autoimmune. Erythroblastosis fetalis: Mother's immune system attacks fetus. An immune system disorder but not autoimmune. Fibrodysplasia ossificans progressiva: Possibly an immune system disorder but not autoimmune.
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Eosinophilic esophagitis (EoE) is an allergic inflammatory condition of the esophagus that involves eosinophils, a type of white blood cell. In healthy individuals, the esophagus is typically devoid of eosinophils. [ 2 ]
Food protein-induced enterocolitis syndrome (FPIES) is a systemic, non IgE-mediated food allergy to a specific trigger within food, most likely food protein.As opposed to the more common IgE food allergy, which presents within seconds with rash, hives, difficulty breathing or anaphylaxis, FPIES presents with a delayed reaction where vomiting is the primary symptom.