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Patients with secondary Raynaud's can also have symptoms related to their underlying diseases. Raynaud's phenomenon is the initial symptom that presents for 70% of patients with scleroderma, a skin and joint disease. [citation needed] When Raynaud's phenomenon is limited to one hand or one foot, it is referred to as unilateral Raynaud's.
CREST syndrome, also known as the limited cutaneous form of systemic sclerosis (lcSSc), is a multisystem connective tissue disorder.The acronym "CREST" refers to the five main features: calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia.
This list includes conditions that are not diseases, but symptoms or syndromes common to autoimmune disease. [118] Chronic fatigue syndrome; Complex regional pain syndrome; Eosinophilic esophagitis; Gastritis; POEMS syndrome [119] Raynaud's phenomenon; Primary immunodeficiency [120] Pyoderma gangrenosum
Raynaud’s phenomenon, which causes parts of the body like the fingers and the toes to go cold and numb, likely stems from two genes, a study published Thursday in the journal Nature ...
Most patients (over 80%) have vascular symptoms and Raynaud's phenomenon, which leads to attacks of discoloration of the hands and feet in response to cold. Raynaud's normally affects the fingers and toes. Systemic scleroderma and Raynaud's can cause painful ulcers on the fingers or toes, which are known as digital ulcers.
The most prevalent skin change is Raynaud's phenomenon, which usually appears early in the course of the disease. [14] Swollen digits are a common sign, and on occasion, the complete hand swells. [15] [16] Acrosclerosis, also known as sclerodactyly, can develop with or without proximal scleroderma and is usually a later symptom of the condition ...
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In extreme cases, the affected person may lose fingers. The effects are cumulative. When symptoms first appear, they may disappear after a short time. If exposure to vibration continues over months or years, the symptoms can worsen and become permanent. [4] Exposure to hand arm vibrations is a respectively newer occupational hazard in the work ...