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Lecithin has been shown to effectively decrease cholesterol concentration by 33%, lower LDL by 38% and increase HDL by 46%. [5] [non-primary source needed] Phytosterols may be found naturally in plants. Similar to ezetimibe, phytosterols reduce the absorption of cholesterol in the gut, so they are most effective when consumed with meals.
As lipid-lowering medications, statins are effective in lowering LDL cholesterol; they are widely used for primary prevention in people at high risk of cardiovascular disease, as well as in secondary prevention for those who have developed cardiovascular disease. [2] [3] [4]
Bempedoic acid, which was approved in 2020 by the Food and Drug Administration, is not as effective as statins, which are considered the gold standard in treating high cholesterol. However, many ...
An experimental drug helped lower bad cholesterol by as much as 50% in a recent study. andresr/Getty Images This article originally appeared on Healthline.
Statins are a popular cholesterol-reducing medication, but come with a risk of muscle aches and other uncomfortable side effects. New research finds that bempedoic acid may be an effective ...
Bezafibrate (marketed as Bezalip and various other brand names) is a fibrate drug used as a lipid-lowering agent to treat hyperlipidaemia. It helps to lower LDL cholesterol and triglyceride in the blood, and increase HDL. It was patented in 1971 and approved for medical use in 1978. [1]
VICTORION-1-PREVENT is the only dedicated study of a non-statin lipid-lowering therapy in a high-risk primary prevention population as defined by American College of Cardiology and American Heart ...
Pravastatin acts as a lipoprotein-lowering drug through two pathways. In the major pathway, pravastatin inhibits the function of hydroxymethylglutaryl-CoA (HMG-CoA) reductase . As a reversible competitive inhibitor, pravastatin sterically hinders the action of HMG-CoA reductase by occupying the active site of the enzyme.