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In the developing world, parasites are the most common cause. A parasitic infection of nearly any bodily tissue can cause eosinophilia. [citation needed] Diseases that feature eosinophilia as a sign include: Allergic disorders Asthma [34] Hay fever [34] Drug allergies [34] Allergic skin diseases [34] Pemphigus [34] Dermatitis herpetiformis ...
Known causes include certain medications or environmental triggers, parasitic infections, and cancer. Eosinophilic pneumonia can also occur when the immune system attacks the lungs, a disease called eosinophilic granulomatosis with polyangiitis. When a cause cannot be found, the eosinophilic pneumonia is termed "idiopathic". Idiopathic ...
But, perhaps the most common cause for eosinophilia is an allergic condition such as asthma. In 1989, contaminated L-tryptophan supplements caused a deadly form of eosinophilia known as eosinophilia-myalgia syndrome, which was reminiscent of the toxic oil syndrome in Spain in 1981.
Acute eosinophilic pneumonia (AEP) is an uncommon, acute-onset form of eosinophilic lung disease which varies in severity. Though poorly understood, the pathogenesis of AEP likely varies depending on the underlying cause which may include smoking, inhalation exposure, medication, and infection. [ 1 ]
If the cause is unknown, it is specified and called "simple pulmonary eosinophilia". Cardiac damage caused by the damaging effects of eosinophil granule proteins (e.g. major basic protein) is known as Loeffler endocarditis and can be caused by idiopathic eosinophilia or eosinophilia in response to parasitic infection. [12]
Eosinophilia is often prominent in filarial infections. Dead worms may cause chronic abscesses, which may lead to the formation of granulomatous reactions and fibrosis. [citation needed] In the human host, Loa loa larvae migrate to the subcutaneous tissue, where they mature into adult worms in approximately one year, but sometimes up to four ...
Angiostrongylus cantonensis is a nematode (roundworm) parasite that causes angiostrongyliasis, an infection that is the most common cause of eosinophilic meningitis in Southeast Asia and the Pacific Basin. [3] The nematode commonly resides in the pulmonary arteries of rats, giving it the common name rat lungworm. [4]
High parasitic loads or repeated infection can lead to visceral larva migrans (VLM). [5] VLM is primarily diagnosed in young children, because they are more prone to exposure and ingestion of infective eggs. [7] Toxocara infection commonly resolves itself within weeks, but chronic eosinophilia may result. In VLM, larvae migration incites ...