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Parietal cells produce potent hydrochloric acid, which damages cells. Gastric chief cells produce pepsinogen, which is activated by the acid to form pepsin. Pepsin is a protease that can digest and damage stomach cells. To prevent these disastrous effects, mucus and bicarbonate ions (HCO 3 −) are secreted by the foveolar cells.
The anatomy of the foveola was recently reinvestigated. [2] Serial semithin and ultrathin sections, and focused ion beam (FIB) tomography were prepared from 32 foveolae from monkeys (Macaca fascicularis) and humans. Serial sections and FIB analysis were then used to construct 3D models of central Müller and photoreceptor cells. [2]
These cells almost fill the tube and the remaining lumen is continued as a very fine channel. Cells found in the gastric glands include mucous neck cells, chief cells, parietal cells, G cells, and enterochromaffin-like cells (ECLs). The first cells of all of the glands are mucus-secreting foveolar cells that line the gastric pits.
foveolae gastricae: TA98: A05.5.01.032 ... but give way to a series of other types of cells which then line the ... public domain from the 20th edition of Gray's Anatomy
A compact epithelial cell lining. Cells in the epithelium of the stomach are bound by tight junctions that repel harsh fluids that may injure the stomach lining. A special mucus covering, derived from mucus secreted by surface epithelial cells and Foveolar cells. This insoluble mucus forms a protective gel-like coating over the entire surface ...
Diagram of the alkaline mucous layer in the stomach with mucosal defense mechanisms. The gastric mucosa is the mucous membrane layer of the stomach, which contains the gastric pits, to which the gastric glands empty. In humans, it is about one mm thick, and its surface is smooth, soft, and velvety.
Foveolar_cells_-_crop.jpg (463 × 181 pixels, file size: 20 KB, MIME type: image/jpeg) This is a file from the Wikimedia Commons . Information from its description page there is shown below.
The gastric folds consist of two layers: Mucosal layer – This layer releases stomach acid.It is the innermost layer of the stomach. [5] It is affected by the hormone histamine, which signals it to release hydrochloric acid (HCl).